MASSIVE Research Stories: Exploring the Patterns of Brain Connectivity

Professor Michael Breakspear, a psychiatrist and researcher, looks for unifying models to fit the complex neurophysiology of the brain and reveal how the brain works in time and space.

Michael’s research covers wide-ranging aspects of brain function and neural connectivity networks - the so-called ‘brain connectome’. Such knowledge could form the basis of a greater understanding of what can go wrong when the networks do not function properly, for example in schizophrenia, bipolar disorder, depression and dementia.

The handling and analysis of the large data sets generated by his research is ‘computationally intensive’, which is where MASSIVE comes in.

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MASSIVE Research Stories: Australia’s Most Powerful Biological Microscope

Life and health ultimately depend on the interactions of large biological molecules – proteins, lipids, carbohydrates and others. How those interactions are initiated and proceed depends on the 3D shapes and structures of the participating molecules.

In February 2015, Monash University unveiled the most powerful biological microscope in Australia. The microscope is capable of providing detailed images of molecular interactions. The $5 million FEI Titan Krios cryo-Electron Microscope (cryo-EM) will transform the way we view the human immune system, and enable Australian researchers to work towards better treatment for diseases of the immune system, which include cancer, malaria, diabetes, rheumatism and multiple sclerosis.

But the capacity of the new microscope to do its job, which is to provide extremely detailed images, is heavily dependent on how the associated huge amounts of data are processed, stored and analysed. The accurate, reliable handling of all the data hinges on MASSIVE and its integration with the new machine.

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User Newsletter Q1 2015

Welcome to the second of our quarterly newsletters focused on providing important updates to MASSIVE users. In this newsletter we provide essential information on the transition to Centos 6/SLURM and workshops to help with the transition. We provide an update on Avizo software and licensing changes. But firstly we highlight some new information to be found in the MASSIVE User Guide.

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User Newsletter Q4 2014

Welcome to the first of our quarterly newsletters focused on providing important updates to MASSIVE users. In this newsletter we provide essential information on managing CPU allocations and alert you to the upcoming application round of the National Computational Merit Allocation Scheme (NCMAS). We also update you on some major operational initiatives enabling MASSIVE to better serve you into 2015 and beyond. Finally we provide a few tips on making best use of MASSIVE today.

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National Computational Merit Allocation Scheme Call For Applications for 2015

The 2015 application round for the National Computational Merit Allocation Scheme (NCMAS) [opened on] Wednesday 1 October 2014 [and closes on Friday 31 October 2014]. NCMAS is the principal, merit-based access program for allocation of high-performance computing resources in Australia.

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